What
is spasmodic dysphonia?
Spasmodic dysphonia (SD) is a type of dystonia, a neurologic
disease
that causes involuntary movements. There are two types
of
SD. Adductor SD (AdSD) causes the vocal fold to come
together (adduct) inappropriately during voicing, makes
up about 85-90% of SD. Abductor SD (AbSD), on the other
hand, makes the vocal folds come apart (abduct) during
connected speech. These movements cause the symptoms
which are discussed below.
SD usually affects adults, with a typical onset of symptoms
in the 30s and 40s. The cause is unknown, and there do not appear
to be any behaviors or environmental factors that increase the
chance of contracting SD. It is not hereditary.
What
are the symptoms of spasmodic dysphonia?
In
AdSD, the vocal folds come together too tightly during speech,
causing strained,
strangled breaks in the voice. In AbSD, the vocal folds part,
causing breathy or soundless breaks. In both cases, the voice
breaks are irregular, and the severity of the symptoms can vary
from day to day, or even over the course of a single day. It
is typical for anxiety to cause symptoms to be more noticeable.
People with SD often report that speaking with strangers or public
speaking makes the voice worse. Almost all report that using
the phone is especially challenging.
SD, like most dystonias, is task-specific. That is, it is only
evident during one type of activity. Other laryngeal actions,
like breathing and swallowing, are usually unaffected. Sometimes,
the voice will even be fluent while laughing or singing, but
not during connected speech. This feature, combined with the
deterioration of the voice with anxiety, occasionally causes
the disorder to be mistakenly attributed to psychiatric reasons.
SD is not a psychiatric or psychological disease.
What
does spasmodic dysphonia look like?
SD
is a disorder of vocal fold movement, so the larynx has
to be examined during
voicing, and preferably during connected speech. The typical
involuntary motions of the vocal folds are brief and spasm-like
(hence the name “spasmodic”), and may occasionally
be difficult to make out. This is especially true if the examination
is being performed with rigid endoscopy,
which requires the tongue to be pulled forward. Flexible fiberoptic
laryngoscopy is
better than rigid laryngoscopy for diagnosis of SD.
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Diagnosis
of SD made from a person’s description and demonstration
of the problem, and from observation of the vocal folds during
voicing. There is no specific finding on any test that identifies
SD. Ultimately, the diagnosis is a matter of expert opinion.
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How
is spasmodic dysphonia treated?
There is no cure for SD. Treatment is available to improve symptoms, and happily,
that is almost always possible. It is important to understand that choosing not
to get treated does not make the disease worse.
Laryngeal injections of botulinum toxin are the main therapy for
SD. Botulinum toxin is a naturally occurring substance that weakens
muscle for a period of about three months. It is best known as
a cosmetic treatment to remove wrinkles, which it does by weakening
forehead muscles, but botulinum toxin has probably accomplished
the most good as a treatment for disorders of involuntary movement,
like SD. Neither voice therapy, psychological/psychiatric treatment
or medical treatment has by itself been useful in controlling SD
symptoms.
Botulinum toxin has been used to treat SD since 1984. The principle
behind treatment is to weaken the muscles that are behind the inappropriate
motion. In the case of AdSD, these are the muscles that bring the
vocal folds together, and in AbSD, the muscles that bring the vocal
folds apart. The injection is performed through the skin of the
neck as an office procedure. Afterwards, people can usually go
on with the normal activities of the day.
In AdSD, because the muscles that bring the vocal folds together
are weakened, injection is usually followed by a period of breathy,
whispery voice and sometimes coughing while drinking liquids. If
this is severe, or last beyond 7-10 days, the dose of botulinum
toxin may be adjusted. In AbSD, the situation is more complicated,
as overweakening of the muscles that part the vocal folds might
result in difficulty breathing. For the reason, treatment in AbSD
must be more cautious, and overall, symptom control is not as good
as in AdSD.
Over the last thirty years, many surgeons have tried to treat
SD by cutting or altering the nerve supply to the larynx. Early
results have always been encouraging, but for complex reasons probably
having to do with the brain abnormality underlying dystonia, the
disorder returns in people after a few months or years. Currently,
surgery is a second-choice treatment, best reserved for those people
in whom botulinum toxin is, for one reason or another, not possible
or ineffective.
More
information can be obtained from the National
Spasmodic Dysphonia Association (www.dysphonia.org/nsda),
the Dystonia Medical Research
Foundation (www.dystonia-foundation.org),
or from Dr. Sulica’s
office. The treatment of SD is a special interest of Dr. Sulica,
and a focus of his practice.
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